1 / 1
|
DeCS
|
|
|
Descriptor English:
|
|
Agouti Signaling Protein
|
Descriptor Spanish:
|
|
proteína de señalización Agouti
|
Descriptor Portuguese:
|
|
Proteína Agouti Sinalizadora
|
Synonyms English:
|
|
ASIP Protein
Agouti Protein
Agouti Switch Protein
|
Tree Number:
|
|
D12.644.276.049
D12.776.467.049
D23.529.049
|
Definition English:
|
|
A secreted protein of approximately 131 amino acids (depending on species) that regulates the synthesis of eumelanin (brown/black) pigments in MELANOCYTES. Agouti protein antagonizes the signaling of MELANOCORTIN RECEPTORS and has wide distribution including ADIPOSE TISSUE; GONADS; and HEART. Its overexpression in agouti mice results in uniform yellow coat color, OBESITY, and metabolic defects similar to type II diabetes in humans. |
History Note English:
|
|
2008 (1993)
|
Allowable Qualifiers English:
|
|
|
Record Number:
|
|
52758
|
Unique Identifier:
|
|
D054366
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS
|